Remeron
(Mirtazapine)
Remeron is a noradrenergic and
selective serotonergic antidepressant pill introduced by Organon back
in 1994. Mirtazapine, active ingredient in rameron, carries a
dual-action effect rectifying the chemical imbalances in the brain
that are responsible for causing depression. Norepinephrine and
serotonin are two chemicals that are believed to contribute to
depressed mood, poor sleep, anxiety, weight loss, and other symptoms
of depression. Remeron acts by increasing the release of both these
chemicals from nerve cells in the brain, thereby relieving symptoms.
Rameron mirtazapine not only increases
the release of the two chemicals mentioned above, it also blocks two
specific serotonergic receptor sites (5-HT2 and 5-HT3) so that they do
not become stimulated. Remeron's ability to target specific serotonin
receptors makes a significant advancement in the evolution of
bio-chemical selectivity in the brain to treat depression. The ability
to target serotonin receptors is critical, since it minimizes common
side-effects patients typically find undesirable with most other
agents, such as lower sexual desire, nervousness and insomnia.
The Food and Drug Administration FDA
cleared rameron for marketing for the treatment of depression. FDA cleared Remeron on the basis of efficient data from
clinical trials involving approximately 3,000 people. Results from
placebo and amitriptyline-controlled clinical trials supported the
conclusion that Remeron provides effective relief of depression as
stated.
Rameron Mirtazapine is a tetracyclic antidepressant in the same class as maprotiline (Ludiomil). Mirtazapine also acts as an antihistamine similar to diphenhydramine (Benadryl). Mirtazapine adds to the sedative effects of alcohol and other drugs that can cause sedative action such as benzodiazepine class of anti-anxiety drugs (Valium, Ativan, Klonopin, Xanax), the narcotic class of pain medications and its derivatives (Percocet, Vicodin, Dilaudid, Codeine, Darvon), the tricyclic class of antidepressants (Elavil, Tofranil, Norpramin), certain antihypertensive medications (Catapres, Inderal), and some antihistamines (Benadryl; Atarax; Vistaril).
Remeron is a registered trademark of Organon. Information provided on this site is for education purposes only. This site is not affiliated or endorsed with Organon.
